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Rolling Stone

Here’s Why Mushroom Supplements Are Now Part of Our Everyday Routine

Oscar Hartzog and Sage Anderson
5 min read

If you purchase an independently reviewed product or service through a link on our website, Rolling Stone may receive an affiliate commission.

Medicinal mushroom supplements might be a new secret weapon to well-being. Promising a boost to your immune system, healthy antioxidants, improved mood, and even (possible) carcinogen-fighting powers, the best mushroom supplements can seem too good to be true. But they’ve worked for us — and many others too.

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Here’s a full guide on the best mushroom supplements to try right now, plus some key information about the trendy health supplements.

In This Article

The Best Mushroom Supplements to Buy Online

How Do Mushroom Supplements Work?

What Are Mushroom Supplements Good For?

What Are the Best Medicinal Mushrooms?

The Best Mushroom Supplements to Buy Online

Looking to reap the benefits of medicinal mushrooms? Read on for the best mushroom supplements to buy online right now.

Mushrooms like these are also often consumed as a coffee substitute — see our favorite mushroom coffees here.

Editor’s Pick: FreshCap Ultimate Mushroom Complex Capsule

For Mental Clarity: Future Kind Lion’s Mane Mushroom Complex

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Spray Supplement: Supermush Mouth Spray Bundle

Mushroom Design: Multivitamin + Mushrooms Vitamin Formula

Tincture: Wooden Spoon Herbs Mushroom Magic

1. FreshCap Ultimate Mushroom Complex Capsule

mushroom supplement capsules
mushroom supplement capsules

We love FreshCap’s Ultimate Mushroom Complex because it’s a comprehensive mushroom supplement. In addition to improving your immune system, mood, and energy levels, the brand says this mushroom complex is a great way to deal with day-to-day depression and/or anxiety. Plus, the formula only includes mushrooms (no soy, gluten, caffeine, or animal products), so you can take these at any time of day.

FreshCap Ultimate Mushroom Complex Capsule

Price: $35.99

Buy On Amazon

2. Future Kind Lion’s Mane Mushroom Complex

mushroom supplement vegan
mushroom supplement vegan

This supplement from Future Kind helps with energy and immunity, but its primary purpose is cognitive health. Thanks to a large dose of lion’s mane mushroom, the supplement should foster better memory, quicker thinking, and overall brain function. If you’ve been feeling any “brain fog” or forgetfulness (maybe at work), give the supplements a try.

Future Kind Lion’s Mane Mushroom

Price: $19.99

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Buy Now

3. Supermush Mouth Spray Bundle

mushroom supplement spray
mushroom supplement spray

Supermush takes a different approach to mushroom supplements by packaging the formula in a spray bottle. By spraying the supplement into your throat, the ingredients are absorbed faster for more immediate results (the sprays also taste surprisingly good too). For newcomers, we recommend getting Supermush’s sampler pack. It has three different formulas — one for immunity, one for energy, and one to calm down — depending on what you need. All bottles use only adaptogen mushrooms in their formulas, so you know you’re getting a clean dose of health-boosting ‘shrooms.

Supermush Mouth Spray Bundle

Price: $69

Buy Now

4. Mushroom Design Vitamin Formula

mushroom pills
mushroom pills

For comprehensive medicinal mushroom advantages, check out Mushroom Design. The brand’s mushroom multivitamins include nine mushrooms, including cordyceps, lion’s mane, chaga, and reishi, as well as nine vitamins including B, C, and E. Together, these ingredients can totally revamp your well-being with stronger immunity, a better mood, and more energy. Plus, the pills don’t include any excess: there are no animal products, gluten, soy, or synthetics, ensuring safety for any diet.

Mushroom Design Vitamin Formula

Price: $45.99

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Buy On Amazon

5. Wooden Spoon Herbs Mushroom Magic

mushroom tincture supplement
mushroom tincture supplement

Small-batch apothecary Wooden Spoon Herbs offers mushroom supplements that aim to support your immune and nervous systems in a gentle, natural way. The formula for their popular tinctures is dual-extracted — they’re tinctured first, then simmered down to extract all the shroom-y benefits you need. Their Daily Balance blend is made with organic Reishi and Lion’s mane mushrooms for their immune and cognitive support, as well as Maitake mushrooms to encourage a healthy metabolism.

Wooden Spoon Herbs Mushroom Magic

Price: $29

Buy Now

How Do Mushroom Supplements Work?

One of the reasons why so many people are trying mushroom supplements is because they’re simple and straightforward. The best mushroom supplements are just what they sound like: A blend of mushroom extracts, sometimes mixed with vitamins and minerals for added benefits.

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The mushrooms included in these supplements are usually different than the ones you eat. Some supplement formulas do include shiitake or maitake mushrooms, but many of the benefits come from fungi that have long been used for medicinal purposes in the East (more on these types of mushrooms below).

What Are Mushroom Supplements Good For?

Eastern medicine has made use of medicinal mushrooms for millennia, and Western medicine is finally catching up. New studies are proving that mushrooms’ purported superpowers are likely real, such as their ability to treat, and even prevent cancer.

But the best mushroom supplements can also lend day-to-day benefits like better brain function, a healthier immune system, more energy, and better sleep. For the most part, different benefits come from different kinds of medicinal mushrooms, which is why mushroom supplements are so great. By combining multiple mushrooms in one easy-to-take tablet, the best mushroom supplements lend a myriad of health advantages.

Plus, unlike many prescription pills, mushroom supplements are very safe. As a natural medicine, the best mushroom supplements typically have minimal, if any side effects.

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Also, note that medicinal mushrooms are different than the kind that makes you trip; those are psilocybin mushrooms, while these are called adaptogen mushrooms.

What Are the Best Medicinal Mushrooms?

Below are some of the common mushroom varieties you’ll find in the best mushroom supplements, plus their individual benefits as discovered in lab studies and animal testing.

Chaga: Delivering an immune system boost and anti-inflammation powers, chaga mushroom has some proven virtues and has been used by humans for centuries.

Reishi: For mood stabilization and immune health, turn to supplements with reishi mushrooms. Studies indicate that the fungus can help lessen anxiety and depression symptoms and balance energy levels.

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Lion’s Mane: One of the most potent medicinal mushrooms, Lion’s Mane has a range of benefits from inflammation reduction to immunity-boosting and anxiety treatment.

Cordyceps: Cordyceps fungus is uniquely effective for boosting energy, both mentally and physically. It does this by helping the cardiovascular system utilize oxygen more efficiently, thereby upping athletic performance and alertness.

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