The Best Anti-Aging Serums You Can Buy at the DrugstoreErin LukasWed, May 30, 2018 at 1:00 PM UTCRetinol is one of the most effective anti-aging ingredients, but it can also be extremely irritating and drying. This RoC serum mixes the retinoid with antioxidants, making it gentle enough for everyday use. Buy it here for $18.CourtesyOn top of improving the appearance of fine lines and wrinkles, this hydrating drugstore staple prevents future ones from forming and improves skin texture. Buy it here for $20.CourtesyFor under $20, this treatment can make crow's feet and other deep wrinkles less prominent in just a week. While this serum is is extremely affordable, it's also extremely powerful: Start off using it every other day to prevent irritation and flaking. Buy it here for $17.CourtesyThis drugstore staple is formulated with skin-plumping and firming amino acids and peptides that make visible signs of aging, well, a lot less visible. Buy it here for $22.CourtesyThink of this L'Oreal pen as a needle-free alternative to actual filler. Use it to dispense serum wherever you have especially noticeable fine lines. The hyaluronic acid-packed formula plumps them up so that skin appears smooth and more full.Buy it here for $20.CourtesyThe over $40 price of La Roche Posay's serum may exceed the drugstore average, but it's still a steal compared to what you'd find at high-end skincare counters. On top of targeting fine lines and wrinkles, the formula acts as a mild exfoliant, smoothing skin and minimizing pores. Buy it here for $45.CourtesyYou know the old cliché about not judging a book by its cover? The same can be said for this No7 serum bottle. It might look unassuming, but it's filled with potent anti-aging ingredients like peptide matrixyl and antioxidants. With continued use, they improve the appearance of deep lines and wrinkles. Buy it here for $27.Courtesy1 of 81 of 8RoC Retinol Correxion Deep Wrinkle Anti-Aging Facial Serum2 of 8Retinol is one of the most effective anti-aging ingredients, but it can also be extremely irritating and drying. This RoC serum mixes the retinoid with antioxidants, making it gentle enough for everyday use. Buy it here for $18.CourtesyAveeno Active Naturals Absolutely Ageless Intensive Renewal Blackberry3 of 8On top of improving the appearance of fine lines and wrinkles, this hydrating drugstore staple prevents future ones from forming and improves skin texture. Buy it here for $20.CourtesyNeutrogena Rapid Wrinkle Repair Serum With Retinol4 of 8For under $20, this treatment can make crow's feet and other deep wrinkles less prominent in just a week. While this serum is is extremely affordable, it's also extremely powerful: Start off using it every other day to prevent irritation and flaking. Buy it here for $17.CourtesyOlay Regenerist Micro-Sculpting Serum5 of 8This drugstore staple is formulated with skin-plumping and firming amino acids and peptides that make visible signs of aging, well, a lot less visible. Buy it here for $22.CourtesyL'Oreal Paris Revitalift Daily Volumizing Concentrated Serum6 of 8Think of this L'Oreal pen as a needle-free alternative to actual filler. Use it to dispense serum wherever you have especially noticeable fine lines. The hyaluronic acid-packed formula plumps them up so that skin appears smooth and more full.Buy it here for $20.CourtesyLa Roche-Posay Effaclar Pore Refining Anti-Wrinkle Face Cream7 of 8The over $40 price of La Roche Posay's serum may exceed the drugstore average, but it's still a steal compared to what you'd find at high-end skincare counters. On top of targeting fine lines and wrinkles, the formula acts as a mild exfoliant, smoothing skin and minimizing pores. Buy it here for $45.CourtesyNo7 Protect & Perfect Intense Advanced Serum8 of 8You know the old cliché about not judging a book by its cover? The same can be said for this No7 serum bottle. It might look unassuming, but it's filled with potent anti-aging ingredients like peptide matrixyl and antioxidants. With continued use, they improve the appearance of deep lines and wrinkles. Buy it here for $27.CourtesySerums are known for being extremely effective, but they can be expensive. We rounded up the best affordable drugstore anti-aging serums.About Our Ads